Closed-loop estimation of retinal network sensitivity reveals signature of efficient coding

نویسندگان

  • Ulisse Ferrari
  • Christophe Gardella
  • Olivier Marre
  • Thierry Mora
چکیده

According to the theory of efficient coding, sensory systems are adapted to represent natural scenes with high fidelity and at minimal metabolic cost. Testing this hypothesis for sensory structures performing non-linear computations on high dimensional stimuli is still an open challenge. Here we develop a method to characterize the sensitivity of the retinal network to perturbations of a stimulus. Using closed-loop experiments, we explore selectively the space of possible perturbations around a given stimulus. We then show that the response of the retinal population to these small perturbations can be described by a local linear model. Using this model, we computed the sensitivity of the neural response to arbitrary temporal perturbations of the stimulus, and found a peak in the sensitivity as a function of the frequency of the perturbations. Based on a minimal theory of sensory processing, we argue that this peak is set to maximize information transmission. Our approach is relevant to testing the efficient coding hypothesis locally in any context where no reliable encoding model is known.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Managing Environmentally Conscious in Designing Closed-loop Supply Chain for the Paper Industry

High amounts of waste paper are disposed of every year in Iran posing the health hazard and environmental damages instead of being recovered. Collection, recovery and proper disposal of waste paper without damaging the environment need to design an efficient closed-loop supply chain network. The main objective of this paper is introducing a bi-objective, multi-echelon, multi-product and single-...

متن کامل

A Novel Sustainable Closed-loop Supply Chain Network Design by Considering Routing and Quality of Products

One of the strategic decisions that can be made in supply chain is designing its network which has high impact on costs, and satisfaction level of customers. This paper focuses on designing a distribution network including determining the number and location of facilities, how to allocate the customers in network, and also determining the extent of carrying different products from different ori...

متن کامل

A joint pricing-network design model for a resilient closed-loop supply chain under quantity discount

In this paper, a novel resilient multi-echelon closed-loop location-allocation-inventory problem (RMCLIP) is addressed that optimizes strategic and tactical decisions simultaneously. In order to represent the purchasing cost of raw material from the supplier, a pricing model under quantity discounts is employed in the closed-loop supply chain (CLSC). Considering the capability of returning the ...

متن کامل

A Network Design Model for a Resilient Closed-Loop Supply Chain with Lateral Transshipment

This paper develops a model for the closed-loop supply chain network design with disruption risk. By considering supply disruption, two factors including extra inventory and lateral transshipment are used as resilience strategies. The main purpose is to reduce the supply chain costs due to the location decisions, quantity of products between different levels and lost sale. Disruption in a suppl...

متن کامل

A new multi-product closed-loop supply chain network design in dairy industry

Nowadays, manufacturers need to satisfy consumer demands in order to compete in the real world. This requires the efficient operation of supply chain planning. On the other hand, increasing worldwide environmental, lack of food resources and social concerns are motivating manufacturers and consumers to implement recycling strategies such as product recovery, waste management, or usage of recycl...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016